Queen Bee – Online Slang Dictionary: “a woman expressing her leadership; mostly used by females referring to their role as the main and only leader.”
From “Six Things You Didn’t Know about Honey Bees”, by Hilary Kearney: A queen bee has a stinger but only uses it to battle other queens in order to protect her position.
A newly hatched queen will sting her unhatched rivals, killing them while they are still in their cells. If two queens hatch at once, they must fight to the death.